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From A to Z icon

Sandoz One Source for HYRIMOZ® and adalimumab-adaz can help ensure a seamless start or switch

HYRIMOZ® Patient Transition program logo

Ready to make the switch?

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Patients can text "HYRIMOZ PTP" to 1-833-HYRIMOZ to enroll
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They will need to submit a photo of their pharmacy receipt OR medication label OR prescription history from an insurance or pharmacy platform
  • Photo must include:
    • Patient name
    • Date of fill (must be filled within the last 90 days)
    • HYRIMOZ or adalimumab-adaz medication name
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Once their eligibility has been verified, they will receive a healthcare debit card in the mail
A One time $200 reimbursment For eligible patients who switch from Humira® to HYRIMOZ or adalimumab-adaza

Co-pay as low as $0 for eligible, commercially insured patients.

Terms and conditions applyb

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Available to patients prescribed HYRIMOZ and adalimumab-adaz
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Patients can enroll themselves online, via text, or over the phone
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Instant access means cards are available immediately for those who qualify
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No expiration, with automatic annual reset of card benefits
Hyrimoz® adalimumab-adaz SANDOZ one source®, Pay as little as $0 per treatment For questions, call Sandoz One Source Co-Pay Program for Hyrimoz, toll-free at 1-833-HYRIMOZ (1-833-497-4669). Visit www.hyrimoz.com for program eligibility details.

Sandoz One Source for 
HYRIMOZ offers support to you, 
your staff, and your patients

Sandoz One Source logo
3 ways to enroll:
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Enroll Online

Click here to complete the online Sandoz One Source Enrollment Form for ADULT patients

Click here to complete the online Sandoz One Source Enrollment form for PEDIATRIC patients

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Enroll via Fax

Download the Sandoz One Source Enrollment Form for ADULT patients or PEDIATRIC patients and fax the completed form to 1-844-600-0449

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Enroll via Phone

Call 1-833-HYRIMOZ (1-833-497-4669) to speak with a live Sandoz One Source for HYRIMOZ Case Manager

Explore other support services available through Sandoz One Source for HYRIMOZ

HYRIMOZ Field Reimbursement Managers
  • Available to answer questions about patient-levelc reimbursement support and insurance coverage
  • Click here to request a visit
Nurse Ambassadors
  • Help patients understand and navigate the insurance process
  • Identify ways to save on prescription costs
  • Provide support for injection training
  • Click here to complete an enrollment form
Reimbursement Support
  • HYRIMOZ Case Managers assist with benefits investigations and the prior authorization (PA) process
  • Use CoverMyMeds® to complete a PA request via CoverMyMeds (CMM) account
QuickStart Program
  • Addresses PA and appeal delays
  • Provides product support for PA and appeal delays
Injection Training
  • 1:1 in-person and virtual options available
  • Click here to view a video highlighting the Sensoready® pen injection experience. The video is also available on HYRIMOZ.com for you to share with your patients to support a successful injection
Demonstration Kits
  • Experience the Sensoready pen 2-click technology with buttonless activation for yourself
  • Show your patients that the Sensoready pen was designed with them in mind
  • Click here to request delivery of a Sensoready training device
Refill Reminders
  • Patients can sign up for regular reminders via phone call or text
In-Home Support
  • Welcome Packets and sharps containers delivered directly to patients' homes

aThe HYRIMOZ® Patient Transition Program provides a one-time reimbursement of costs to patients who transition from Humira® to HYRIMOZ, in the form of a $200 debit card that the patient must certify will be used for healthcare-related expenses. The following are acceptable merchant codes at which the debit cards can be used: 5912 DRUG STORES, PHARMACIES; 8011 DOCTORS – NOT ELSEWHERE CLASSIFIED; 8050 NURSING AND PERSONAL CARE FACILITIES; 8062 HOSPITALS; 8071 DENTAL AND MEDICAL LABORATORIES; and 8099 HEALTH PRACTITIONERS/MED SVCS UNCLASSIFIED. To qualify, a patient must provide proof of a filled HYRIMOZ prescription for an approved indication dated no more than 90 days prior to applying for the Patient Transition Program. Residents of Illinois, Massachusetts, Michigan, Minnesota, Mississippi, and Rhode Island are not eligible. A patient is not eligible if the patient’s prescription is paid for, in whole or in part, by any state or federally funded programs, including but not limited to Medicare (including Part D, even in the coverage gap) or Medicaid, Medigap, VA, DOD, or TRICARE, or private indemnity, or HMO insurance plans that reimburse the patient for the entire cost of the patient’s prescription drugs, or where prohibited by law. Sandoz reserves the right to rescind, revoke, or amend this offer at any time and without further notice.

bHYRIMOZ Co-pay Terms and Conditions: Limitations apply. Valid only for patients with private insurance and where not prohibited by law. Prescription must be for an approved indication. Program is subject to an annual limit, and the patient is responsible for any costs once limit is reached in a calendar year. Program not valid (i) under Medicare, Medicaid, TRICARE, VA, DoD, or any other federal or state health care program, (ii) where patient is not using insurance coverage at all, (iii) where the patient's insurance plan reimburses for the entire cost of the drug, or (iv) where product is not covered by patient's insurance. The value of this program is exclusively for the benefit of patients and is intended to be credited towards patient out-of-pocket obligations and maximums, including applicable co-payments, coinsurance, and deductibles. Patient may not seek reimbursement for the value received from this program from other parties, including any health insurance program or plan, flexible spending account, or health care savings account. Patient is responsible for complying with any applicable limitations and requirements of their health plan related to the use of the Program. Valid only in the United States and US Territories (Puerto Rico, American Samoa, Guam, Northern Mariana Islands, and US Virgin Islands). This Program is not health insurance, and may not be combined with any third-party rebate, coupon, or offer. Proof of purchase may be required. Sandoz reserves the right to rescind, revoke, or amend the Program and discontinue support at any time without notice.

Cordavis HYRIMOZ Co-pay Terms and Conditions: Limitations apply. Valid only for those with private insurance. Prescription must be for an approved indication. Patient is responsible for any costs once limit is reached in a calendar year. Program not valid (i) under Medicare, Medicaid, TRICARE, VA, DoD, or any other federal or state health care program, (ii) where patient is not using insurance coverage at all, (iii) where the patient's insurance plan reimburses for the entire cost of the drug, or (iv) where product is not covered by patient's insurance. The value of this program is exclusively for the benefit of patients and is intended to be credited towards patient out-of-pocket obligations and maximums, including applicable co-payments, coinsurance, and deductibles.

The HYRIMOZ® Co-pay Terms and Conditions have restrictions when insurance entities limit what can be counted towards your deductible or other costs you bear when buying your medication. The most common names are “co-pay accumulator” or “co-pay maximizer” programs. These programs may be implemented without your awareness. In some cases, there may be a negative financial impact. The use of “co-pay accumulator” or “co-pay maximizer” programs by your insurer or health plan will limit your program benefits. These limits can be modified without prior notice. Cordavis reserves the right to audit and investigate any suspected violation of these terms and conditions. Cordavis also has the right to modify these terms and conditions at any time without prior notice.

Program is not valid where prohibited by law. Patient may not seek reimbursement for the value received from this Program from other parties, including any health insurance program or plan, flexible spending account, or health care savings account. Patient is responsible for complying with any applicable limitations and requirements of their health plan related to the use of the Program. Valid only in the United States and U.S. Territories (Puerto Rico, Guam, Northern Mariana Islands, and Virgin Islands). This Program is not health insurance. Program may not be combined with any third-party rebate, coupon, or offer. Proof of purchase may be required. Cordavis reserves the right to rescind, revoke, or amend the Program and discontinue support at any time without notice.

cPatient consent must be on file.

Additional offerings include other financial support options such as a patient assistance program and independent co-pay foundations.

Please call 1-833-HYRIMOZ to speak with a Sandoz One Source for HYRIMOZ Case Manager to learn more.

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Important Safety Information and Indications

INDICATIONS: HYRIMOZ® (adalimumab-adaz) injection for subcutaneous use, a prescription medication, is a tumor necrosis factor (TNF)-blocker indicated for:

  • Rheumatoid Arthritis (RA): Alone or in combination with methotrexate or other non-biologic disease-modifying anti-rheumatic drugs (DMARDs), for reducing signs and symptoms, inducing major clinical response, inhibiting the progression of structural damage, and improving physical function in adult patients with moderately to severely active RA
  • Juvenile Idiopathic Arthritis (JIA): Alone or in combination with methotrexate for reducing signs and symptoms of moderately to severely active polyarticular JIA in patients 2 years of age and older
  • Psoriatic Arthritis (PsA): Alone or in combination with non-biologic DMARDs, for reducing signs and symptoms, inhibiting the progression of structural damage, and improving physical function in adult patients with active PsA
  • Ankylosing Spondylitis (AS): Reducing signs and symptoms in adult patients with active AS
  • Crohn’s Disease (CD): Treatment of moderately to severely active CD in adults and pediatric patients 6 years of age and older
  • Ulcerative Colitis (UC): Treatment of moderately to severely active UC in adult patients
    Limitations of use: The effectiveness of adalimumab products has not been established in patients who have lost response to or were intolerant to TNF blockers.
  • Plaque Psoriasis (Ps): The treatment of adult patients with moderate to severe chronic Ps who are candidates for systemic therapy or phototherapy, and when other systemic therapies are medically less appropriate. HYRIMOZ should only be administered to patients who will be closely monitored and have regular follow-up visits with a physician
  • Hidradenitis Suppurativa (HS): HYRIMOZ is indicated for the treatment of moderate to severe HS in adults
  • Uveitis: Treatment of non-infectious intermediate, posterior, and panuveitis in adults

IMPORTANT SAFETY INFORMATION:

WARNING: SERIOUS INFECTIONS AND MALIGNANCY

SERIOUS INFECTIONS

Patients treated with adalimumab products, including HYRIMOZ, are at increased risk for developing serious infections that may lead to hospitalization or death. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids.

Discontinue HYRIMOZ if a patient develops a serious infection or sepsis.

Reported infections include:

  • Active tuberculosis (TB), including reactivation of latent TB. Patients with TB have frequently presented with disseminated or extrapulmonary disease. Test patients for latent TB before HYRIMOZ use and during therapy. Initiate treatment for latent TB prior to HYRIMOZ use
  • Invasive fungal infections, including histoplasmosis, coccidioidomycosis, candidiasis, aspergillosis, blastomycosis, and pneumocystosis. Patients with histoplasmosis or other invasive fungal infections may present with disseminated, rather than localized, disease. Antigen and antibody testing for histoplasmosis may be negative in some patients with active infection. Consider empiric anti-fungal therapy in patients at risk for invasive fungal infections who develop severe systemic illness
  • Bacterial, viral, and other infections due to opportunistic pathogens, including Legionella and Listeria

Carefully consider the risks and benefits of treatment with HYRIMOZ prior to initiating therapy in patients with chronic or recurrent infection.

Monitor patients closely for the development of signs and symptoms of infection during and after treatment with HYRIMOZ, including the possible development of TB in patients who tested negative for latent TB infection prior to initiating therapy.

MALIGNANCY

Lymphoma and other malignancies, some fatal, have been reported in children and adolescent patients treated with TNF blockers including adalimumab products. Post-marketing cases of hepatosplenic T-cell lymphoma (HSTCL), a rare type of T-cell lymphoma, have been reported in patients treated with TNF-blockers including adalimumab products. These cases have had a very aggressive disease course and have been fatal. The majority of reported TNF blocker cases have occurred in patients with Crohn's disease or ulcerative colitis and the majority were in adolescent and young adult males. Almost all these patients had received treatment with azathioprine or 6-mercaptopurine (6–MP) concomitantly with a TNF blocker at or prior to diagnosis. It is uncertain whether the occurrence of HSTCL is related to use of a TNF blocker or a TNF blocker in combination with these other immunosuppressants.

WARNINGS AND PRECAUTIONS

Serious Infections

  • Do not start HYRIMOZ during an active infection, including localized infections
  • If an infection develops, monitor carefully, and stop HYRIMOZ if infection becomes serious. Drug interactions with biologic products: A higher rate of serious infections has been observed in RA patients treated with rituximab who received subsequent treatment with a TNF blocker. An increased risk of serious infections has been seen with the combination of TNF blockers with anakinra or abatacept, with no demonstrated added benefit in patients with RA. Concomitant administration of HYRIMOZ with other biologic DMARDs (eg, anakinra or abatacept) or other TNF blockers is not recommended based on the possible increased risk for infections and other potential pharmacological interactions
  • Patients 65 years of age and older, patients with co-morbid conditions and/or patients taking concomitant immunosuppressants, may be at greater risk of infection
  • Invasive fungal infections: For patients who develop a systemic illness on HYRIMOZ, consider empiric antifungal therapy for those who reside or travel to regions where mycoses are endemic

Malignancies

  • In clinical trials, incidence of malignancies was greater in adalimumab-treated patients than in controls
  • Consider the risks and benefits of TNF blocker-treatment, including HYRIMOZ, prior to initiating therapy in patients with known malignancy
  • Non-melanoma skin cancer (NMSC) was reported during clinical trials for adalimumab-treated patients. Examine all patients, particularly those with a history of prolonged immunosuppressant or PUVA therapy for the presence of NMSC prior to and during treatment with HYRIMOZ
  • In the adalimumab clinical trials there was an approximate 3-fold higher rate of lymphoma than expected in the general US population. Patients with chronic inflammatory diseases, particularly those with highly active disease and/or chronic exposure to immunosuppressant therapies, may be at a higher risk than the general population for the development of lymphoma, even in the absence of TNF blockers
  • Post-marketing cases of acute and chronic leukemia have been reported in association with TNF-blocker use. Approximately half of the post-marketing cases of malignancies in children, adolescents, and young adults receiving TNF blockers were lymphomas; other cases represented a variety of different malignancies and included rare malignancies usually associated with immunosuppression and malignancies that are not usually observed in children and adolescents

Hypersensitivity Reactions

  • Anaphylaxis or serious allergic reactions have been reported following administration of adalimumab products. If an anaphylactic or other serious hypersensitivity reaction occurs, immediately discontinue administration of HYRIMOZ and institute appropriate therapy

Hepatitis B Virus Reactivation

  • Use of TNF blockers, including HYRIMOZ, may increase the risk of reactivation of hepatitis B virus (HBV) in patients who are chronic carriers. Some cases have been fatal
  • Evaluate patients at risk for HBV infection for prior evidence of HBV infection before initiating TNF blocker therapy
  • Exercise caution in patients identified as carriers of HBV and closely monitor during and after HYRIMOZ treatment
  • In patients who develop HBV reactivation, stop HYRIMOZ and initiate effective anti-viral therapy. Exercise caution when resuming HYRIMOZ after HBV treatment

Neurologic Reactions

  • Use of TNF-blocking agents, including adalimumab products, has been associated with rare cases of new onset or exacerbation of central nervous system and peripheral demyelinating disease, including multiple sclerosis (MS), optic neuritis, and Guillain-Barré syndrome
  • Exercise caution when considering HYRIMOZ for patients with these disorders; discontinuation of HYRIMOZ should be considered if any of these disorders develop
  • There is a known association between intermediate uveitis and central demyelinating disorders

Hematological Reactions

  • Rare reports of pancytopenia, including aplastic anemia, have been reported with TNF-blocking agents. Medically significant cytopenia has been infrequently reported with adalimumab products
  • Consider stopping HYRIMOZ if significant hematologic abnormalities occur

Heart Failure

  • Worsening and new onset congestive heart failure (CHF) has been reported with TNF blockers. Cases of worsening CHF have also been observed with adalimumab products; exercise caution and monitor carefully

Autoimmunity

  • Treatment with adalimumab products may result in the formation of autoantibodies and, rarely, in the development of a lupus-like syndrome. Discontinue treatment if symptoms of a lupus-like syndrome develop

Immunizations

  • Patients on HYRIMOZ should not receive live vaccines
  • Pediatric patients, if possible, should be brought up to date with all immunizations prior to initiating HYRIMOZ therapy
  • Adalimumab is actively transferred across the placenta during the third trimester of pregnancy and may affect immune response in the in utero exposed infant. The safety of administering live or live-attenuated vaccines in infants exposed to adalimumab products in utero is unknown. Risks and benefits should be considered prior to vaccinating (live or live-attenuated) exposed infants

ADVERSE REACTIONS

The most common adverse reactions (incidence >10 %): infections (eg, upper respiratory, sinusitis), injection site reactions, headache, and rash.

Please see full Prescribing Information for HYRIMOZ, including Boxed Warning and Medication Guide.

To report SUSPECTED ADVERSE REACTIONS, contact Sandoz Inc. at 1-800-525-8747 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.